Epigenetic Remodeling by Vitamin C Potentiates the Differentiation of Mouse and Human Plasma Cells
H.-Y. Chen, A. Almonte-Loya, F.-Y. Lay, E. Johnson, E. Gonzalez-Avalos, J. Yin, Q. Ma, D. J. Wozniak, F. E. Harrison, C.-W. J. Lio
This study shows vitamin C enhances plasma cell differentiation in mouse and human B cells by epigenetic remodeling via TET enzymes and STAT3-dependent mechanisms.
bioRxiv · Sep 15, 2021 · PreprintImmunology