Author

C.-W. J. Lio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Almonte-Loya· 1 shared A. G. Freud· 1 shared A. Rao· 1 shared A. Saadey· 1 shared A. Varkey· 1 shared C. D. Eisele· 1 shared D. J. Wozniak· 1 shared D. M. Jones· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperImmunology

A. Almonte-Loya

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3 papers

Recent·Most cited

Aiolos modulates the TFH and CD4-CTL differentiation programs via reciprocal regulation of the Zfp831/TCF-1/Bcl-6 axis and CD25

K. A. Read, D. M. Jones, S. Pokhrel, E. D. S. Hales, A. Varkey, J. A. Tuazon, C. D. Eisele, O. Abdouni, A. Saadey, R. T. Warren, M. D. Powell, J. M. Boss, E. A. Hemann, J. S. Yount, H. E. Ghoneim, , K. J. Oestreich

This study identifies Aiolos as a regulator of TFH and CD4-CTL differentiation, showing it modulates the Zfp831/TCF-1/Bcl-6 axis and suppresses the cytotoxic gene program.

bioRxiv · May 18, 2022 · PreprintImmunology

Epigenetic Remodeling by Vitamin C Potentiates the Differentiation of Mouse and Human Plasma Cells

H.-Y. Chen, A. Almonte-Loya, F.-Y. Lay, E. Johnson, E. Gonzalez-Avalos, J. Yin, Q. Ma, D. J. Wozniak, F. E. Harrison, C.-W. J. Lio

This study shows vitamin C enhances plasma cell differentiation in mouse and human B cells by epigenetic remodeling via TET enzymes and STAT3-dependent mechanisms.

bioRxiv · Sep 15, 2021 · PreprintImmunology

Loss of TET proteins in regulatory T cells unleashes effector function

X. Yue, C.-W. J. Lio, D. Samaniego-Castruita, X. Li, A. Rao

This study shows that loss of TET2 and TET3 in regulatory T cells leads to immune dysfunction and inflammation in mice.

bioRxiv · Feb 15, 2019 · PreprintImmunology