Author

F. Fricke

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Biology Disciplines

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

C. Liesche· 1 shared J. Beaudouin· 1 shared J. Berndt· 1 shared M. Heilemann· 1 shared R. Eils· 1 shared S. Aschenbrenner· 1 shared

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2018-2018 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCell Biology

C. Liesche

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1 paper

Recent·Most cited

CD95 receptor activation by ligand-induced trimerization is independent of its partial pre-ligand assembly

C. Liesche, J. Berndt, F. Fricke, S. Aschenbrenner, M. Heilemann, R. Eils, J. Beaudouin

This paper investigates how CD95 receptor activation occurs through ligand-induced trimerization, showing that receptor multimerization follows ligand binding while FADD recruitment is delayed, and that soluble CD95L is a poor inducer of apoptosis due to inefficient FADD recruitment.

bioRxiv · Apr 2, 2018 · PreprintCell Biology