Author

F. Frolow

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Pharmacology & Toxicology· 1

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Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

D. Gordon· 1 shared E. Reuveny· 1 shared G. Panyi· 1 shared H. Altman-Gueta· 1 shared I. Karbat· 1 shared M. Gurevitz· 1 shared O. Dym· 1 shared S. Fine· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

D. Gordon

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1 paper

Recent·Most cited

Pore-modulating toxins exploit inherent slow inactivation to block K+ channels

I. Karbat, H. Altman-Gueta, S. Fine, T. Szanto, S. Hamer-Rogotner, O. Dym, F. Frolow, D. Gordon, G. Panyi, M. Gurevitz, E. Reuveny

The paper shows that the toxin Cs1 blocks K+ channels by modulating pore structure through hydrogen bond disruption, leading to asymmetric pore collapse.

bioRxiv · Mar 13, 2019Pharmacology & Toxicology