SUMO Modifies GβL and Mediates mTOR Signaling
S. L. L. Park, U. N. Ramirez Jarquin, N. Shahani, O. Rivera, M. Sharma, F. P. McManus, P. Thibault, S. Subramaniam
This study identifies SUMO modification of GβL as a regulator of mTOR complex assembly and activity, showing that SUMOylation is essential for proper mTOR signaling.
bioRxiv · Sep 3, 2020Biochemistry