Biosynthesis of aurodox, a Type III secretion system inhibitor from Streptomyces goldiniensis
R. E. McHugh, J. T. Munnoch, R. E. Braes, I. J. W. McKean, J. M. Giard, A. Taladriz-Sender, F. Peschke, G. A. Burley, A. J. A. Roe, P. A. Hoskisson
This paper characterizes the aurodox biosynthetic gene cluster in Streptomyces goldiniensis and identifies key enzymatic steps responsible for its anti-virulence activity against EHEC.
bioRxiv · Feb 14, 2022Microbiology