Identification of the 216kbp gene cluster and structure elucidation of gargantulides B and C, new complex 52-membered macrolides from Amycolatopsis sp.
D. Carretero-Molina, F. J. Ortiz-Lopez, T. Gren, D. Oves-Costales, J. Martin, F. Roman-Hurtado, T. S. Jorgensen, M. de la Cruz, C. Diaz, F. Vicente, K. Blin, F. Reyes, T. Weber, O. Genilloud
This study identifies a 216 kbp gene cluster and elucidates the structures of gargantulides B and C, new 52-membered macrolides from Amycolatopsis sp., revealing their biosynthetic pathway and antibacterial activity.
bioRxiv · Aug 11, 2021 · PreprintMicrobiology