Establishment of a screening platform based on human coronavirus OC43 for the identification of microbial natural products with antiviral activity
B. Martinez-Arribas, F. B. Annang, R. Diaz-Gonzalez, G. Perez-Moreno, J. Martin, T. A. Mackenzie, F. Castillo, F. Reyes, O. Genilloud, L. M. Ruiz-Perez, F. Vicente, M. C. Ramos, D. Gonzalez-Pacanowska
This paper establishes a high-throughput screening platform using HCoV-OC43 to identify microbial natural products with antiviral activity, identifying 10 extracts with potential new compounds and confirming antiviral activity in others.
bioRxiv · Apr 20, 2023Microbiology