Author

F. V. Filipp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

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Assay:bulk RNA-seq· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Aublin-Gex· 1 shared B. Panthu· 1 shared C. Jacquemin· 1 shared D. M. Tveit· 1 shared D. Weddle· 1 shared G. Fjeld· 1 shared G. J. P. Rautureau· 1 shared J. W. Palmer· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

A. Aublin-Gex

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4 papers

Recent·Most cited

Spatial cancer systems biology resolves heterotypic interactions and identifies disruption of spatial hierarchy as a pathological driver event

F. V. Filipp

The paper uses spatially annotated single-cell data to analyze PCP factors in melanoma, identifying dysregulated developmental programs as drivers of metastatic progression.

bioRxiv · Mar 1, 2023Cancer Biology

The relationship between PD-L1 and quiescence in melanocyte stem cell aging.

J. W. Palmer, K. M. Villavicencio, M. Idris, D. Weddle, F. V. Filipp, NISC Comparative Sequencing Program - NHGRI, W. J. Pavan, M. L. Harris

This study shows that PD-L1 expression is a feature of quiescent melanocyte stem cells and that PD-L1-expressing cells are more retained with age.

bioRxiv · Sep 22, 2022 · PreprintCell Biology

Lipogenesis and innate immunity in hepatocellular carcinoma cells reprogrammed by an isoenzyme switch of hexokinases

L. Perrin-Cocon, P.-O. Vidalain, C. Jacquemin, A. Aublin-Gex, K. Olmstead, B. Panthu, G. J. P. Rautureau, P. Andre, P. Nyczka, M.-T. Hutt, N. Amoedo, R. Rossignol, F. V. Filipp, V. Lotteau, O. Diaz

This study shows that switching hexokinase isoenzymes in HCC cells alters metabolism and reactivates innate immunity, improving survival outcomes.

bioRxiv · Mar 13, 2020 · PreprintCancer Biology

Exploring Mechanisms of Glucose Uptake Regulation and Dilution Resistance in Growing Cancer Cells

D. M. Tveit, G. Fjeld, T. Drengstig, F. V. Filipp, P. Ruoff, K. Thorsen

This paper uses mathematical modeling and gene expression data to show that controlling intermediate glycolytic enzymes is necessary for dilution resistance in cancer cells.

bioRxiv · Jan 2, 2020 · PreprintCancer Biology