Author

D. Weddle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Akinc· 1 shared A. B. Castoreno· 1 shared A. Kasper· 1 shared A. Rogers· 1 shared A. Sahakyan· 1 shared A. Simon· 1 shared C. Hebner· 1 shared C. R. Brown· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Akinc

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2 papers

Recent·Most cited

The relationship between PD-L1 and quiescence in melanocyte stem cell aging.

J. W. Palmer, K. M. Villavicencio, M. Idris, D. Weddle, F. V. Filipp, NISC Comparative Sequencing Program - NHGRI, W. J. Pavan, M. L. Harris

This study shows that PD-L1 expression is a feature of quiescent melanocyte stem cells and that PD-L1-expressing cells are more retained with age.

bioRxiv · Sep 22, 2022 · PreprintCell Biology

Robust and durable prophylactic protection conferred by RNA interference in preclinical models of SARS-CoV-2

Y. I. Anglero-Rodriguez, F. A. Lempp, J. McIninch, M. K. Schlegel, C. R. Brown, D. J. Foster, A. B. Castoreno, T. Nguyen, M. Subramanian, M. Montiel-Ruiz, H. Kaiser, A. Sahakyan, R. Spreafico, S. S. Morskaya, J. D. Barry, , V. Jadhav

This study identifies two siRNA combinations that provide robust prophylactic protection against SARS-CoV-2 in hamsters by reducing viral load and preventing lung pathology.

bioRxiv · Mar 20, 2022 · PreprintPharmacology & Toxicology