Author

P.-O. Vidalain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Amara· 2 shared A. Peres de Oliveira· 2 shared F. Tangy· 2 shared J.-F. Eleouët· 2 shared L. Bonnet-Madin· 2 shared L. Meertens· 2 shared M. Galloux· 2 shared V. Lotteau· 2 shared

Activity by Year

2020-2021 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

A. Amara

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Respiratory Syncytial virus NS1 protein targets the transactivator binding domain of MED25

V. Basse, J. Dong, A. Peres de Oliveira, P.-O. Vidalain, F. Tangy, M. Galloux, J.-F. Eleouët, C. Sizun, M. Bajorek

This paper identifies the interaction between RSV NS1 and MED25's ACID domain, showing NS1 competes with ATF6 to inhibit innate immune gene transcription.

bioRxiv · Nov 19, 2021 · PreprintMicrobiology

RACK1 associates with RNA-binding proteins Vigilin and SERBP1 to control dengue virus replication

A. Brugier, M.-L. Hafirassou, M. Pourcelot, M. Baldaccini, L. Couture, V. Kril, B. Kuemmerer, S. Gallois-Montbrun, L. Bonnet-Madin, S. Pfeffer, P.-O. Vidalain, C. Delaugerre, L. Meertens, A. Amara

This study identifies RACK1 as a host factor that recruits Vigilin and SERBP1 to facilitate dengue virus replication by linking viral RNA to the translation machinery.

bioRxiv · Oct 28, 2021 · PreprintMicrobiology

Depletion of TAX1BP1 amplifies innate immune responses during respiratory syncytial virus infection

D. Descamps, A. Peres de Oliveira, L. Gonnin, S. Madrieres, J. Fix, C. Drajac, Q. Marquant, E. Bouguyon, V. Pietralunga, H. Iha, A. Morais Ventura, F. Tangy, P.-O. Vidalain, J.-F. Eleouët, M. Galloux

This study shows that TAX1BP1 depletion enhances innate immune responses during RSV infection, suggesting it as a potential antiviral target.

bioRxiv · Jun 3, 2021Microbiology

Characterization and functional interrogation of SARS-CoV-2 RNA interactome

A. Labeau, A. Lefevre-Utile, L. Bonnet-Madin, L. Fery-Simonian, V. Soumelis, V. Lotteau, P.-O. Vidalain, A. Amara, L. Meertens

This study identifies 142 RNA-binding proteins interacting with SARS-CoV-2 RNA and finds many are proviral, offering potential drug targets for antiviral therapies.

bioRxiv · Mar 23, 2021Microbiology

Replication of Equine arteritis virus is efficiently suppressed by purine and pyrimidine biosynthesis inhibitors

j.-c. Valle-Casuso, D. Gaudaire, L. Martin-Faivre, a. madeline, P. Dallemagne, S. Pronost, H. Munier-Lehmann, S. Zientara, P.-O. Vidalain, A. Hans

This study identifies three compounds that suppress EAV replication in equine cells, including ribavirin and DHODH inhibitors, offering potential antiviral strategies for EAV outbreaks.

bioRxiv · Apr 10, 2020Microbiology

Lipogenesis and innate immunity in hepatocellular carcinoma cells reprogrammed by an isoenzyme switch of hexokinases

L. Perrin-Cocon, P.-O. Vidalain, C. Jacquemin, A. Aublin-Gex, K. Olmstead, B. Panthu, G. J. P. Rautureau, P. Andre, P. Nyczka, M.-T. Hutt, N. Amoedo, R. Rossignol, F. V. Filipp, V. Lotteau, O. Diaz

This study shows that switching hexokinase isoenzymes in HCC cells alters metabolism and reactivates innate immunity, improving survival outcomes.

bioRxiv · Mar 13, 2020 · PreprintCancer Biology