Broadly reactive human monoclonal antibodies targeting the pneumococcal histidine triad protein protect against fatal pneumococcal infection
J. Huang, A. D. Gingerich, F. Royer, A. V. Paschall, A. Pena-Briseno, F. Y. Avci, J. J. Mousa
The paper isolates human monoclonal antibodies against pneumococcal proteins PhtD and PspA, showing protection against pneumococcal infection in mice.
bioRxiv · Feb 17, 2021Immunology