Comparison of the tolerability of 161Tb- and 177Lu-labeled somatostatin analogues in the preclinical setting
Sarah D. Busslinger, Ana Katrina Mapanao, Kristel Kegler, Peter Bernhardt, Fabienne Flühmann, Julia Fricke, Jan Rijn Zeevaart, U. Köster, Nicholas P. van der Meulen, Roger Schibli, Cristina Müller
This study compares the tolerability of 161Tb- and 177Lu-labeled somatostatin analogues in mice, finding that SSTR antagonists caused more hematologic changes than agonists, but both were safe at therapeutic activity levels.
European Journal of Nuclear Medicine and Molecular Imaging · Jul 24, 2024Peer-reviewedCancer Biology