A humanized neuronal model system reveals key roles for manganese in neuronal endocytosis, calcium flux and mitochondrial bioenergetics
Dimitri Budinger, Sharmin Alhaque, Ramón González‐Méndez, Chris Dadswell, Katy E Barwick, Arianna Ferrini, Charlotte Roth, Conor J. McCann, Karin Tuschl, Fatma Al Jasmi, Maha Saad Zaki, Julien H. Park, Russell Clive Dale, Shekeeb S. Mohammad, John Christodoulou, , Manju A. Kurian
The paper establishes a humanized neuronal model to investigate the effects of manganese dysregulation on neuronal function and disease mechanisms.
bioRxiv · Nov 27, 2024 · PreprintNeuroscience