Author

Chris Dadswell

University of SussexORCID 0000-0002-5564-5223Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Organism:zebrafish· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Karin TuschliD· 3 shared Ramón González‐MéndeziD· 3 shared Jason RiheliD· 2 shared Leonardo E. ValdiviaiD· 2 shared Stephen W. WilsoniD· 2 shared Ahad A. RahimiD· 1 shared Amy F. GeardiD· 1 shared Andrew McGowniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersNeuroscience

Karin TuschlORCID

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3 papers

Recent·Most cited

Pharmacology & ToxicologyBiochemical PharmacologyPeer-reviewedSep 11, 2026

A novel pipeline for the validation of manganese chelators for the treatment of manganese overload

Hendrik Vogt, Chiara Pojani, Jack Devonport…·Karin Tuschl

This paper develops a pipeline to identify and evaluate novel manganese chelators using zebrafish and mouse models, finding that H3PyC3A and Me3PyC3A show improved manganese mobilization and reduced accumulation.

1 citation

zebrafishmouse

NeurosciencebioRxivPreprintNov 27, 2024

A humanized neuronal model system reveals key roles for manganese in neuronal endocytosis, calcium flux and mitochondrial bioenergetics

Dimitri Budinger, Sharmin Alhaque, Ramón González‐Méndez…·Manju A. Kurian

The paper establishes a humanized neuronal model to investigate the effects of manganese dysregulation on neuronal function and disease mechanisms.

1 citation

humanbulk RNA-seq

NeuroscienceDisease Models & MechanismsPeer-reviewedMay 6, 2022

Loss of slc39a14 causes simultaneous manganese deficiency and hypersensitivity in zebrafish

Karin Tuschl, Richard Joseph White, Chintan A. Trivedi…·Elisabeth M. Busch‐Nentwich

The paper identifies manganese deficiency and neurotoxicity in zebrafish slc39a14 mutants through transcriptome analysis, revealing key molecular pathways involved in manganese homeostasis disruption.

18 citations

zebrafishbulk RNA-seq