Differential Effects of Mutations of Popeye Domain Containing Proteins on Heteromeric Interaction and Membrane Trafficking
Alexander H. Swan, Roland F. R. Schindler, Marco Savarese, Isabelle Mayer, Susanne Rinné, Felix Bleser, Anne Schänzer, Andreas Hahn, Mario Sabatelli, Francesco Perna, Kathryn Chapman, Mark A. Pfuhl, Alan C. Spivey, Niels Decher, Bjarne Udd, , Thomas Brand
This study investigates how mutations in POPDC proteins affect their heteromeric interaction and membrane trafficking, finding that complex formation is essential for membrane targeting.
bioRxiv · Oct 13, 2022 · PreprintGenetics