Author

Anne Schänzer

Justus-Liebig-Universität GießenORCID 0000-0002-2014-2028Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alan C. SpiveyiD· 1 shared Alexander H. SwaniD· 1 shared Amparo Acker‐PalmeriD· 1 shared Andreas HahniD· 1 shared Andreas HentscheliD· 1 shared Andreas RoosiD· 1 shared Andrew Lee MammeniD· 1 shared Benedikt G. H. SchoseriD· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperGenetics

Alan C. SpiveyORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Vascular FLRT2 regulates venous-mediated angiogenic expansion and CNS barriergenesis

Cecília Llaó-Cid, Blanca Peguera, Piotr Kobialka, Linda Decker, Johanna Vogenstahl, Nensi Alivodej, Shubhi Srivastava, J. Jin, Bettina C. Kirchmaier, C. Milla, Hannah Schlierbach, Anne Schänzer, Till Acker, Marta Segarra, Amparo Acker‐Palmer

This study identifies FLRT2 as a critical regulator of venous-mediated angiogenesis and blood-brain barrier formation in the developing mouse CNS.

Nature Communications · Nov 28, 2024Peer-reviewedNeuroscience

Mitochondrial leakage and mtDNA damage trigger early immune response in Inclusion Body Myositis.

Felix Kleefeld, Emily Cross, Daniel Lagos, Benedikt G. H. Schoser, Andreas Hentschel, Tobias Ruck, Christopher Nelke, Sara Walli, Katrin Hahn, Denisa Hathazi, Andrew Lee Mammen, María Casal-Domínguez, Marta Ortova Gut, Ivo Glynne Gut, Simon Charles Heath, , Rita Horváth

This study identifies mitochondrial dysfunction and mtDNA damage as early triggers of immune response in PM-Mito and IBM, linking mitochondrial abnormalities to inflammation and disease progression.

bioRxiv · Aug 5, 2024 · PreprintNeuroscience

Differential Effects of Mutations of Popeye Domain Containing Proteins on Heteromeric Interaction and Membrane Trafficking

Alexander H. Swan, Roland F. R. Schindler, Marco Savarese, Isabelle Mayer, Susanne Rinné, Felix Bleser, Anne Schänzer, Andreas Hahn, Mario Sabatelli, Francesco Perna, Kathryn Chapman, Mark A. Pfuhl, Alan C. Spivey, Niels Decher, Bjarne Udd, , Thomas Brand

This study investigates how mutations in POPDC proteins affect their heteromeric interaction and membrane trafficking, finding that complex formation is essential for membrane targeting.

bioRxiv · Oct 13, 2022 · PreprintGenetics