Structural Elucidation and Revised Biosynthetic Pathway of the Membrane Vesicle-Associated Antifungal Compound AFC
Inês Tavares, Yi‐Chi Chen, Kirsty Agnoli, Michael Berger, Felix Hartrampf, Simon Sieber, Karl Gademann, Leo Eberl
This study determines the structure of the antifungal compound AFC and revises its biosynthetic pathway, showing it is derived from cis-vaccenic acid via ω-modification rather than citric acid conjugation.
Journal of the American Chemical Society · Sep 6, 2026Peer-reviewedBiochemistry