Leo Eberl

This study determines the structure of the antifungal compound AFC and revises its biosynthetic pathway, showing it is derived from cis-vaccenic acid via ω-modification rather than citric acid conjugation.

The paper investigates a gene cluster that produces both enantiomerically pure and racemic metabolites through a stereodivergent pathway involving a dihydrosydnone N-oxide intermediate.

This study designs and synthesizes leudiazen analogs that inhibit Pseudomonas syringae virulence without killing the bacteria, reducing resistance risk.