Author

Felix Krüger

Babraham Institute

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Genomics· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Fabrizio OlmedaiD· 1 shared Laura J. BensoniD· 1 shared Steffen RulandsiD· 1 shared Stephen J. ClarkiD· 1 shared Tim LohoffiD· 1 shared Wolf ReikiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperGenomics

Fabrizio OlmedaORCID

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1 paper

Recent·Most cited

Inference of emergent spatio-temporal processes from single-cell sequencing reveals feedback between de novo DNA methylation and chromatin condensates

Fabrizio Olmeda, Tim Lohoff, Stephen J. Clark, Laura J. Benson, Felix Krüger, Wolf Reik, Steffen Rulands

This paper develops a framework to infer spatio-temporal processes in the nucleus from single-cell methylome data, showing feedback between DNA methylation and chromatin condensates during pluripotency exit.

bioRxiv · Dec 30, 2020 · PreprintGenomics