Homogeneous antibody-DNA-conjugates using unmodified oligonucleotides and photo-crosslinkable protein G-HUH endonuclease fusion proteins
Anna Świetlikowska, Femi Hesen, Alexander Gräwe, Maarten Merkx
This paper introduces a method to create homogeneous antibody-DNA conjugates using unmodified oligonucleotides and photo-crosslinkable protein G-HUH endonuclease fusion proteins, achieving 1:1 stoichiometry.
Bioconjugate Chemistry · May 13, 2026Peer-reviewedBioengineering