Curcumin activates distinct programming of redox metabolism towards differential regulation of gene expression mediated by Nrf1 and Nrf2
Reziyamu Wufuer, Feng Jing, Shaofan Hu, Meng Wang, Liu Keli, Yiguo Zhang
This study investigates how curcumin modulates Nrf1 and Nrf2 expression and their roles in redox metabolism and gene regulation in HepG2 cells and xenograft tumors.
bioRxiv · Jul 9, 2025 · PreprintCancer Biology