Engineering Treg-mediated immune tolerance via foxp3a overexpression to evade allograft transplantation barriers in zebrafish
Junwen Zhu, Yongkang Hao, Fenghua Zhang, Xinyi Gao, Houpeng Wang, Liqun Yu, Xiaosi Wang, Yonghua Sun
This paper demonstrates that overexpressing Foxp3a in zebrafish induces Treg-mediated immune tolerance, enabling efficient transplantation of gonadal primordia and germline stem cells.
Journal of genetics and genomics/Journal of Genetics and Genomics · Mar 3, 2026Peer-reviewedGenetics