Spatial Transcriptomics Reveals that the Local Immune Response to Placental Guinea Pig Cytomegalovirus Infection is Driven by Chemokine Signaling
Zachary W. Berkebile, Colleen L. Forster, Emma Stanley, Fernanda M. Rodriguez, Adam Herman, Micah D. Gearhart, Craig J. Bierle
This study uses spatial transcriptomics to show that GPCMV infection disrupts placental function by altering chemokine signaling and antiviral defense in specific regions.
bioRxiv · Aug 1, 2025 · PreprintImmunology