Adam Herman

This study identifies CD4+ T cells as drivers of fibrosis in MASH by showing their proinflammatory activity and the therapeutic potential of targeting the OX40L-OX40 axis.

CryoMesh enables long-term clinical-scale preservation of human pancreatic and stem cell-derived islets with maintained function and viability for diabetes therapy.

This study shows that macrophage-derived CCL24 worsens fibrosis and cardiac dysfunction in heart failure by activating fibroblasts through the CCR3 receptor.

This study uses spatial transcriptomics to show that GPCMV infection disrupts placental function by altering chemokine signaling and antiviral defense in specific regions.

The paper benchmarks polygenic scores in a large cohort, identifies top-performing models, and provides a public platform for PGS analysis and interpretation.

The paper develops an ensemble fusion-calling pipeline to improve the detection of clinically relevant gene fusions in pediatric cancer, identifying 67 fusions with a 29.3% diagnostic yield.

This paper presents the genome of the zebra mussel, Dreissena polymorpha, providing insights into its invasive success and creating a resource for invasive species research.