Pharmacology & ToxicologybioRxivPreprint
Unexpected Loss of Sensitivity to the nAChR Antagonist Activity of Mecamylamine and DHβEin Nicotine-Tolerant C57BL/6J Mice
Fernando B. de Moura, Lance R. McMahon
The paper examines how chronic nicotine exposure affects the ability of nAChR antagonists to counteract nicotine's effects in mice, finding reduced antagonism during treatment.
DOI 10.1101/482075