SQSTM1/p62 accumulation is a hallmark of FLCN loss in Birt-Hogg-Dube syndrome-associated kidney cancer
Halvor Ullern, Julie Aarmo Johannessen, Feyza Kasikci, Miriam Formica, Naghmeh Karimi Melve, Siri Andresen, Andreas Brech, Karol Axcrona, Kjersti Jørgensen, Lóránt Farkas, Jorrit M. Enserink, Helene Knævelsrud
The paper shows SQSTM1/p62 accumulates in BHD kidney tumors due to FLCN loss, but is not required for tumor growth.
bioRxiv · Jan 14, 2026 · PreprintCancer Biology