Author

Fides D. Lay

Amgen (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1

Frequent Co-Authors

Jasmine TatiD· 2 shared Nathan E. LewisiD· 2 shared Cleo KontoravdiiD· 1 shared Elçin IçteniD· 1 shared Fabrice SchlegeliD· 1 shared Jennitte L. StevensiD· 1 shared Jennitte Stevens· 1 shared Jonathan Diep· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersSystems Biology

Jasmine TatORCID

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2 papers

Recent·Most cited

SEC-seq reveals translation-focused metabolic strategies for high IgG productivity in clonal CHO cells

Jasmine Tat, Fides D. Lay, Jennitte Stevens, Nathan E. Lewis

The paper uses SEC-seq to analyze metabolic and secretory strategies in CHO cells, finding that high IgG-producing clones use distinct translation-focused metabolic states.

Metabolic Engineering · Sep 16, 2026Peer-reviewedSystems Biology

Multi-omic characterization of antibody-producing CHO cell lines elucidates metabolic reprogramming and nutrient uptake bottlenecks

Saratram Gopalakrishnan, William Johnson, Miguel Á. Valderrama-Gómez, Elçin Içten, Jasmine Tat, Fides D. Lay, Jonathan Diep, Natalia V. Gomez, Jennitte L. Stevens, Fabrice Schlegel, Pablo A. Rolandi, Cleo Kontoravdi, Nathan E. Lewis

Metabolic Engineering · Jul 22, 2024Peer-reviewedSystems Biology