Immunological liver-skin axis: a systemic Vγ4+ γδT17 cell responselinks psoriasis-like inflammation and MASLD
Janik Fleissner, Yamila Rocca, Lukas Freund, Thomas Ossner, Fabian Imdahl, Rémi Doucet-Ladevèze, Florian Kurz, Andreas Geier, M. Goebeler, Georg Gasteiger, Andreas Kerstan
This study identifies Vγ4+ γδT17 cells as a link between psoriasis and MASLD, showing their role in systemic inflammation and hepatic remodeling, with clinical relevance of IL-17-targeted therapy.
bioRxiv · Dec 23, 2025 · PreprintImmunology