Non-canonical contribution of human Dicer helicase domain in antiviral innate immune response
Morgane Baldaccini, Léa Gaucherand, Béatrice Chane-Woon-Ming, Mélanie Messmer, Floriane Gucciardi, Sébastien Pfeffer
The paper investigates the role of Dicer's helicase domain in antiviral immunity, finding that a truncated mutant acts RNAi-independently via PKR and NF-kB pathways.
The EMBO Journal · Jan 29, 2024Peer-reviewedMolecular Biology