The non-canonical thioreductase TMX2 is essential for neuronal survival during embryonic brain development
Jordy Dekker, Wendy Lam, Herma C. van der Linde, Floris Ophorst, Charlotte de Konink, Rachel Schot, Gert‐Jan Kremers, Leslie E. Sanderson, Woutje M. Berdowski, Geeske M. van Woerden, Grazia M. S. Mancini, Tjakko J. van Ham
This study shows TMX2 is essential for newborn neuron survival during zebrafish embryonic brain development, with loss causing rapid cell death and calcium dysregulation.
bioRxiv · Jun 18, 2024 · PreprintDevelopmental Biology