Author

Wendy Lam

Altos Labs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Organism:zebrafish· 1

Frequent Co-Authors

Amber NolaniD· 1 shared Benjamin A. YangiD· 1 shared Charlotte de KoninkiD· 1 shared Elma S. FriasiD· 1 shared Floris Ophorst· 1 shared Geeske M. van WoerdeniD· 1 shared Gert‐Jan KremersiD· 1 shared Grazia M. S. ManciniiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Amber NolanORCID

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2 papers

Recent·Most cited

Fate mapping of peripherally derived macrophages reveals a long-lasting engrafted population that maintains a distinct transcriptomic profile for up to 8 months after Traumatic Brain Injury

Maria Serena Paladini, Benjamin A. Yang, Kristof A. Torkenczy, Elma S. Frias, Xi Feng, Karen Krukowski, Rene V. Sit, Maurizio Morri, Wendy Lam, Valentina Pedoia, Stefka Tyanova, Marco Colonna, Amber Nolan, Susanna Rosi

This study tracks the fate of monocyte-derived macrophages (MDMs) after traumatic brain injury (TBI) and finds they persist in the brain for up to 8 months, maintaining a distinct transcriptomic profile and phagocytic activity.

Nature Communications · Oct 7, 2025Peer-reviewedImmunology

The non-canonical thioreductase TMX2 is essential for neuronal survival during embryonic brain development

Jordy Dekker, Wendy Lam, Herma C. van der Linde, Floris Ophorst, Charlotte de Konink, Rachel Schot, Gert‐Jan Kremers, Leslie E. Sanderson, Woutje M. Berdowski, Geeske M. van Woerden, Grazia M. S. Mancini, Tjakko J. van Ham

This study shows TMX2 is essential for newborn neuron survival during zebrafish embryonic brain development, with loss causing rapid cell death and calcium dysregulation.

bioRxiv · Jun 18, 2024 · PreprintDevelopmental Biology