Integrative Multi-omic Profiling of Two Human Decedents Receiving Pig Heart Xenografts Reveals Strong Perturbations in Early Immune-Cell and Cellular Metabolism Responses.
Eloi Schmauch, Brian Piening, Bo Xia, Chenchen Zhu, Jeffrey M. Stern, Weimin Zhang, Alexa K. Dowdell, Bao‐Li Loza, Maedeh Mohebnasab, Loren A. Gragert, Karen Khalil, Brendan R. Camellato, Michelli F. Oliveira, Darragh Patrick O'Brien, Elaina P. Weldon, , Brendan J. Keating
The paper analyzes multi-omic data from two pig heart xenografts in human decedents to identify immune and metabolic responses associated with rejection and injury.
bioRxiv · Jun 5, 2023 · PreprintSystems Biology