Brendan J. Keating

This study examines the association between maternal and fetal HLA heterozygosity and preeclampsia risk in a large multi-ancestry cohort, finding protective and risk associations for specific HLA loci.

This study compares cardiac transcriptome and glucose metabolism markers in human and mouse HFpEF, finding greater conservation in right ventricles and sex-specific differences in left ventricles.

This study tracks T cell clonotypes across tissues in a pig-to-human kidney xenotransplantation model, showing coordinated immune responses preceding xenograft rejection.

The paper analyzes multi-omic data from two pig heart xenografts in human decedents to identify immune and metabolic responses associated with rejection and injury.

LoFTK automatically predicts LoF variants and identifies genes affected by compound heterozygous LoF variants in genomes.

This study performs a large GWAS on dilated cardiomyopathy, identifying two new loci and confirming two existing ones, with potential therapeutic implications.

This study investigates whether genetic predisposition to medical conditions linked to preeclampsia risk increases preeclampsia risk, finding associations with diastolic blood pressure and BMI.