Application of long-read sequencing for robust identification of correct alleles in genome edited animals
Christopher V. McCabe, Peter D. Price, Gemma F. Codner, Alasdair J. Allan, Adam Caulder, Skevoulla Christou, Jorik Loeffler, Matthew Mackenzie, Elke Malzer, Joffrey Mianné, Krystian J. Nowicki, Edward J. O’Neill, Fran J. Pike, Marie Hutchison, Benoit Petit‐Demoulière, , Lydia Teboul
This study uses long-read sequencing to accurately identify correct alleles in genome-edited animals despite mosaicism and complex edits.
PLoS Genetics · Mar 8, 2024Peer-reviewedMolecular Biology