Brain-specific Gata4 downregulation in Greywick female mice models the metabolic subtype of polycystic ovary syndrome
Sherin Ali Nawaito, Mostafa Esmael, Ouliana Souchkova, Tatiana Cardinal, Guillaume Bernas, Karl‐F. Bergeron, Fanny Gayda, Francis Bergeron, Marie‐France Bouchard, Xiang Zhou, Luisina Ongaro, Daniel J. Bernard, Jacob Short, Susan Wray, Robert S. Viger, , Nicolas Pilon
This study shows that Gata4 downregulation in the hypothalamus of Greywick female mice models the metabolic subtype of PCOS by affecting fertility and food intake genes.
The FASEB Journal · Jun 14, 2025Peer-reviewedPhysiology