Author

Francisca Leal

Harvard University

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Evolutionary Biology· 1

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Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

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David Peréz Guerra· 1 shared Johannes v. LintigiD· 1 shared Misty R. RiddleiD· 1 shared Sepalika BandaraiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperEvolutionary Biology

David Peréz Guerra

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1 paper

Recent·Most cited

Adaptive Disruption of Carotenoid Metabolism in Cavefish via Loss of Beta-carotene oxygenase 2a (Bco2a)

David Peréz Guerra, Sepalika Bandara, Francisca Leal, Johannes v. Lintig, Misty R. Riddle

This study shows that loss-of-function mutations in Bco2a in cavefish lead to increased carotenoid and vitamin A accumulation, providing a physiological advantage in low-oxygen environments.

bioRxiv · Oct 6, 2025 · PreprintEvolutionary Biology