Author

Franck Lager

Institut Cochin, CNRS, INSERM, Paris Cité University, Paris, France;Primary ORCID profile (0000-0001-7748-9754 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Franck LageriD1 paper · Centre National de la Recherche Scientifique

Biology Disciplines

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Genetics· 1

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Agnes Rotig· 1 shared Benedetta RuzzenenteiD· 1 shared Clovis Gaborit· 1 shared Federico Mingozzi· 1 shared Gilles Renault· 1 shared Marcelo Simon-Sola· 1 shared Marina Cavazzana· 1 shared Metodi MetodieviD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

Agnes Rotig

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1 paper

Recent·Most cited

GeneticsbioRxivPreprintNov 13, 2026

LRPPRC gene replacement therapy preserves cardiac function and prevents premature death in a mouse model of mitochondrial disease

Sofia Zanin, Franck Lager, Marcelo Simon-Sola…·Benedetta Ruzzenente

This study demonstrates that AAV-mediated LRPPRC gene replacement in mice prevents cardiac dysfunction and extends survival in a mitochondrial disease model.

DOI 10.64898/2026.11.12.762002

mouseexperimental assay

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