Trisomy 21 Impairs Development of Enteric Neural Crest-Derived Cells via SOD1-Mediated RET Dysregulation
Karan Singh, Frank Liu, Andy Zhao, Iman Lohraseb, Teresa Davoli
This study shows Trisomy 21 impairs enteric neural crest development by reducing RET expression through SOD1-mediated oxidative stress.
bioRxiv · Aug 4, 2026 · PreprintCell Biology