The antiviral GTPase MxB is packaged into virions and binds via its N-terminal domain to alphaherpesvirus capsids
Sebastian Weigang, Manutea Christophe Serrero, Boris Bogdanow, Franziska Hüsers, Julia Lückel, Rudolf Bauerfeind, Fan Liu, Georg Kochs, Beate Sodeik
The paper shows that MxB's N-terminal domain binds to herpesvirus capsids and is packaged into virions, restricting HSV-1 and PrV infections.
PLoS Pathogens · Jul 16, 2026Peer-reviewedMolecular Biology