Boris Bogdanow

Phosphorylation-tuned condensation links HCMV tegument assembly to membrane recruitment

This study shows that phosphorylation-regulated condensation of the HCMV protein pp150 couples tegument assembly to membrane recruitment, supporting viral replication.

Virion-wide interactome mapping of HSV-1 reveals maturation-dependent remodeling and convergent organization of herpesvirus tegument networks

This study maps HSV-1 virion-wide protein interactions, revealing maturation-driven network remodeling and conserved organizational principles across herpesviruses.

Snapshot of in-cell protein contact sites reveals new host factors and hijacking of paraspeckles during influenza A virus infection

The paper maps virus-host protein contact sites during influenza A virus infection, revealing new interactions and paraspeckle disassembly as a novel infection mechanism.

The antiviral GTPase MxB is packaged into virions and binds via its N-terminal domain to alphaherpesvirus capsids

The paper shows that MxB's N-terminal domain binds to herpesvirus capsids and is packaged into virions, restricting HSV-1 and PrV infections.

Integrative structural interactomics reveals protein organization and structure in a giant virus

The paper integrates structural and proteomic methods to characterize the protein organization of a giant virus, identifying sub-compartments and membrane protein topologies.

PROTEOME-SCALE RECOMBINANT STANDARDS AND A ROBUST HIGH-SPEED SEARCH ENGINE TO ADVANCE CROSS-LINKING MS-BASED INTERACTOMICS

The paper develops recombinant protein standards and a search engine for XL-MS, showing Scout outperforms existing tools in speed, sensitivity, and false-discovery rate control.

The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant

This study identifies M segment RNA splicing as a determinant of host range in influenza A virus by comparing human- and bird-adapted strains.