Thiol depletion and disruption of proteostasis contribute to the phytotoxicity of juglone
George W. Meyer, Mearaj A. Shaikh, Frederick Mildenhall, MaKenzie R Drowns, Chase T Hearn, Xiaojin Wang, Chao‐Jan Liao, Venkatesh P. Thirumalaikumar, Kranthi Varala, Joshua R. Widhalm
This study investigates how juglone affects Arabidopsis thaliana by depleting thiols and disrupting proteostasis, revealing its phytotoxic mechanisms.
bioRxiv · Apr 13, 2026 · PreprintPlant Biology