Targeting CD38 effectively prevents myelofibrosis in myeloproliferative neoplasms
Yiru Yan, Jinqin Liu, Songyang Zhao, Fuhui Li, Lin Yang, Zefeng Xu, Tiejun Qin, Xiaofan Zhu, Wenbin An, Gang Huang, Raajit K. Rampal, Zhijian Xiao, Bing Li
This study shows that targeting CD38 in monocytes prevents myelofibrosis in MPN models and identifies CD38 as a potential biomarker and therapeutic target.
bioRxiv · Mar 2, 2025 · PreprintCancer Biology