ERas-Null Mice Generated Directly from Embryonic Stem Cells in a Lipid-rich Medium Enable the Discovery of A Novel Role in Craniofacial Development
Yiren Qin, Qiyu Tian, Hoyoung Chung, Fuqian Geng, Daylon James, Jianlong Wang, Duancheng Wen
The paper demonstrates that lipid-rich 2iLA medium enables the generation of ERas-null all-ESC mice, revealing a novel role for ERas in craniofacial development.
bioRxiv · Nov 1, 2023 · PreprintDevelopmental Biology