Yiren Qin

This study creates a multiplex-edited mouse model with woolly mammoth hair traits, showing curly and textured coats through gene modifications.

The paper demonstrates that lipid-rich 2iLA medium enables the generation of ERas-null all-ESC mice, revealing a novel role for ERas in craniofacial development.

The paper generates bat induced pluripotent stem cells and finds they contain endogenous viral sequences, suggesting a deep entanglement between bats and viruses.

The paper shows that adding lipid-rich albumin to 2i media maintains genomic stability and developmental potency of murine pluripotent stem cells over long-term culture.

This paper describes a method to generate clonal male and female mice using CRISPR/Cas9 to delete the Y chromosome in embryonic stem cells, enabling tetraploid complementation to produce viable mice.

This study corrects a mutation in achondroplasia patient-derived iPSCs using CRISPR-Cas9 and restores their chondrogenic differentiation ability.