HCR-FlowFISH: A flexible CRISPR screening method to identify cis-regulatory elements and their target genes
Steven K. Reilly, Sager J. Gosai, Alejandro Gutiérrez, Jacob C. Ulirsch, Masahiro Kanai, Daniel Berenzy, Susan Kales, G E Butler, Adrianne D. Gladden, Hilary K. Finucane, Pardis Christine Sabeti, Ryan Tewhey
HCR-FlowFISH identifies cis-regulatory elements and their target genes by quantifying gene expression changes after CRISPR perturbations, using >270,000 perturbations to detect CREs for multiple genes.
bioRxiv · May 11, 2020 · PreprintGenomics