Molecular BiologyNature CommunicationsPeer-reviewed
Metamorphism of catalytic domain controls transposition in Tn3 family transposases
Alexander V. Shkumatov, Nicolas Aryanpour, Cédric A. Oger…·Rouslan G. Efremov
The paper describes cryo-EM structures of Tn3 family transposase TnpA, revealing a unique catalytic domain refolding mechanism that regulates transposition and target immunity.
34 citations