MicrobiologybioRxiv
Characterization of antimalarial activity of artemisinin-based hybrid drugs
D. R. M. Moreira, H. C. Quadros, L. Herrmann…·S. Tsogoeva
This study characterizes the antimalarial activity of two artemisinin-based hybrid drugs against drug-sensitive and resistant Plasmodium falciparum parasites, finding that slow peroxide bond homolysis correlates with increased efficacy against resistant strains.
DOI 10.1128/aac.00143-24