mTORC3 activity is regulated by GSK3β through the activation of PKCδ that phosphorylates and activates STAT1.
J. Zhan, F. C. Harwood, M. Cardone, G. C. Grosveld
The paper identifies a novel GSK3β/PKCδ/STAT1 pathway that regulates ETV7 transcription and mTORC3 activity in Karpas cells.
bioRxiv · Jan 26, 2024Cell Biology