Author

M. Cardone

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

F. C. Harwood· 2 shared G. C. Grosveld· 2 shared J. Zhan· 2 shared A. I. Lamond· 1 shared A. Phillips· 1 shared P. Halder· 1 shared R. Kriwacki· 1 shared S. T. Have· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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2 shared papersCancer Biology

F. C. Harwood

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2 papers

Recent·Most cited

Assembly of mTORC3 involves binding of ETV7 to two separate sequences in the mTOR kinase domain.

J. Zhan, F. C. Harwood, S. T. Have, A. I. Lamond, P. Halder, R. Kriwacki, G. C. Grosveld, A. Phillips, M. Cardone

This study identifies mTORC3, a rapamycin-resistant mTOR complex that requires ETV7 binding, and shows that specific mTOR and ETV7 domains mediate this interaction, with implications for cancer therapy.

bioRxiv · Mar 19, 2024Cancer Biology

mTORC3 activity is regulated by GSK3β through the activation of PKCδ that phosphorylates and activates STAT1.

J. Zhan, F. C. Harwood, M. Cardone, G. C. Grosveld

The paper identifies a novel GSK3β/PKCδ/STAT1 pathway that regulates ETV7 transcription and mTORC3 activity in Karpas cells.

bioRxiv · Jan 26, 2024Cell Biology